Our research interests include the neurobiology of learning and emotional memory and the mechanisms and roles of neuromodulation in large neural networks. We use a multi-disciplinary approach that includes in vitro, in vivo and computational techniques.

optoThe experimental aspects of this research are conducted using a combination of in vitro and in vivo techniques in the rat. We use state of the art neurophysiology techniques that include two-way real-time brain-machine interfaces and "hyperdrives" allowing for the simultaneous recordings from over 50 neurons in the behaving animal. We also recently started using optogenetic tools to manipulate neural activity in vivo using light, and the use of a small robot that interacts with the rats!

The theoretical aspects of our work involves the use of computational modeling techniques to simulate the activity of single cells and networks of interconnected cells. These computer simulations reproduce and explain experimental data, and generate predictions that can in turn be tested experimentally.